Dimethylamine

Dimethylamine

SCHEMBL11048217

CNC.COc1ccccc1C(c1ccccc1OC)C(C)C

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA12 O43570 1/20 0.48
CA4 P22748 1/20 0.48
CA14 Q9ULX7 1/20 0.48
ACHE P22303 1/20 0.47
CYP2D6 P10635 2/20 0.42
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
LPAR1 Q92633 1/20 0.41
CYP2C19 P33261 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
ADRA2B P18089 1/20 0.40
PTGS1 P23219 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KCNK3 O14649 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL10778485 0.85 CA1 (0.42) CA1CA2CA7CA9CA12
SCHEMBL8177107 0.81 MEN1 (0.52) CYP2D6CYP2C19ALDH1A1TP53KMT2A
SCHEMBL27666009 0.80 MEN1 (0.49) CYP2C19ALDH1A1KMT2AL3MBTL1SLC6A4
SCHEMBL11885435 0.78 CA1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL15473849 0.77 CYP2D6 (0.61) CA1CA2CA7CA9CA12
SCHEMBL20376231 0.77 CYP2D6 (0.61) CA1CA2CA7CA9CA12
SCHEMBL2401390 0.77 CYP2D6 (0.61) CA1CA2CA7CA9CA12
SCHEMBL19268063 0.76 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL14218067 0.76 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL141647 0.75 CA1 (0.60) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431722-A POLYCYCLIC QUINONE PIGMENT DISPERSED IN A RESIN BINDER AS CHARGE GENERATING LAYER; ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-02-14 US disclosed
US-4302521-A TRANSPORT PHASE OF A P-TYPE ORGANIC SEMICONDUCTOR, POLYVINYLCARBAZOLE, A LEWIS AND A BRONSTED ACID; CHARGE TRANSFER COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-11-24 US disclosed