Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30514 | 0.95 | — | — | |
| Hydrogen Peroxide SCHEMBL9436488 | 0.95 | CA1 (0.40) | CA1CA2CA9ACHEFFAR3 | |
| SCHEMBL30960095 | 0.95 | CA1 (0.40) | CA1CA2CA9ACHEFFAR3 | |
| SCHEMBL7749080 | 0.90 | — | — | |
| SCHEMBL1155717 | 0.90 | CA1 (0.36) | CA1CA2CA9ACHEFFAR3 | |
| SCHEMBL1690429 | 0.90 | CA1 (0.36) | CA1CA2CA9ACHEFFAR3 | |
| Ammonia Solution, Strong SCHEMBL1160872 | 0.90 | CA1 (0.36) | CA1CA2CA9ACHEFFAR3 | |
| SCHEMBL4876131 | 0.90 | — | — | |
| SCHEMBL4235388 | 0.90 | CA1 (0.36) | CA1CA2CA9ACHEFFAR3 | |
| SCHEMBL29082708 | 0.90 | CA1 (0.36) | CA1CA2CA9ACHEFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429092-A | COPPER AND TIN PROMOTER, CHAIN TRANSFER MERCAPTAN | U.S. PEROXYGEN COMPANY (US) | 1984-01-31 | — | — | US | disclosed |