Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 10/20 | 0.74 |
| ▸ | EP300 | Q09472 | 9/20 | 0.65 |
| ▸ | FNTA | P49354 | 1/20 | 0.64 |
| ▸ | FNTB | P49356 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049208 | 1.00 | KAT8 (0.74) | KAT8EP300FNTAFNTBMEN1 | |
| SCHEMBL12417244 | 0.87 | KAT8 (0.66) | KAT8EP300FNTAFNTBMEN1 | |
| SCHEMBL13780749 | 0.87 | KAT8 (0.72) | KAT8EP300FNTAFNTBMEN1 | |
| SCHEMBL12691864 | 0.85 | KAT8 (1.00) | KAT8EP300FNTAFNTBMEN1 | |
| SCHEMBL11049070 | 0.82 | KMT2A (0.71) | KAT8EP300FNTAFNTBMEN1 | |
| SCHEMBL12451640 | 0.81 | MAPT (0.83) | KAT8EP300FNTAFNTBMEN1 | |
| SCHEMBL420591 | 0.81 | KAT8 (0.81) | KAT8EP300MEN1KMT2AMAPT | |
| SCHEMBL443203 | 0.81 | KAT8 (0.81) | KAT8EP300MEN1KMT2AMAPT | |
| SCHEMBL8078405 | 0.81 | KAT8 (0.81) | KAT8EP300MEN1KMT2AMAPT | |
| SCHEMBL12451620 | 0.80 | KAT8 (0.65) | KAT8EP300FNTAFNTBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021513-B1 | PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING DISPERSED LIGHT-ABSORBING MEROSTYRYL DYES | AGFA-GEVAERT N.V. (BE) | 1984-03-21 | — | — | EP | disclosed |
| US-4311787-A | Photographic silver halide materials containing dispersed light-absorbing merostyryl dyes | AGFA-GEVAERT, N.V. (BE) | 1982-01-19 | — | — | US | disclosed |
| EP-0021513-A1 | Photographic silver halide materials containing dispersed light-absorbing merostyryl dyes | AGFA-GEVAERT N.V. (BE) | 1981-01-07 | — | — | EP | disclosed |