Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | PPOX | P50336 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047739 | 0.92 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11043256 | 0.88 | TDP1 (0.59) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11053019 | 0.84 | MEN1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11052290 | 0.83 | MEN1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11048553 | 0.80 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10692395 | 0.80 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11262239 | 0.80 | TDP1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11361554 | 0.80 | TDP1 (0.62) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11217304 | 0.80 | TDP1 (0.64) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10554944 | 0.79 | MEN1 (0.69) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043801-B1 | 2-SUBSTITUTED 5-PHENOXY-PHENYL-PHOSPHINIC-ACID DERIVATIVES WITH HERBICIDAL ACTIVITY, PROCESS FOR PREPARING THEM, HERBICIDAL COMPOSITIONS CONTAINING THEM AND USE OF THESE ACTIVE SUBSTANCES AND COMPOSITIONS | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |
| US-4434108-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| EP-0043801-A2 | 2-Substituted 5-phenoxy-phenyl-phosphinic-acid derivatives with herbicidal activity, process for preparing them, herbicidal compositions containing them and use of these active substances and compositions | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |