Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.86 |
| ▸ | PGR | P06401 | 4/20 | 0.86 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.86 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | AR | P10275 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049798 | 1.00 | NR3C2 (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11049793 | 1.00 | NR3C2 (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11581396 | 0.96 | HIF1A (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11581392 | 0.96 | HIF1A (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11582912 | 0.94 | NR3C2 (0.87) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11584200 | 0.94 | NR3C2 (0.87) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11581184 | 0.93 | NR3C2 (0.89) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Resocortol Butyrate SCHEMBL2110603 | 0.93 | NR3C2 (0.89) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11581192 | 0.93 | NR3C2 (0.89) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11753088 | 0.93 | NR3C2 (0.85) | NR3C2PGRNR3C1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56025200-A | — | — | None | — | — | JP | disclosed |
| US-4427591-A | TOPICAL ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1984-01-24 | — | — | US | disclosed |
| US-4336200-A | 17α-Acyloxy-5β-corticoids | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4318853-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| JP-S5625200-A | PREPARATION OF HYDROCORTISONE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1981-03-10 | — | — | JP | disclosed |