Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 10/20 | 0.74 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1534272 | 0.98 | HTR2B (0.76) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL30608416 | 0.98 | HTR2B (0.76) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL1686982 | 0.98 | HTR2B (0.76) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL26117247 | 0.98 | HTR2B (0.76) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL15602812 | 0.87 | HTR2B (0.59) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL15602915 | 0.87 | HTR2B (0.59) | HTR2BGPR35HTR1DHTR7HTR3A | |
| Pulicatins G SCHEMBL12469063 | 0.85 | HTR2B (1.00) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL3993320 | 0.85 | HTR2B (0.74) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL11925403 | 0.85 | HTR2B (0.74) | HTR2BGPR35HTR1DHTR7HTR3A | |
| SCHEMBL3993242 | 0.85 | HTR2B (0.74) | HTR2BGPR35HTR1DHTR7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457936-A | ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |