SCHEMBL11050840

SCHEMBL11050840

C[C@H]1C[C@@H](CN)C(C)(C)C1.N[Pt](Cl)(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052012 0.93
SCHEMBL26607529 0.90 EPHX2 (0.31)
SCHEMBL11047191 0.85
SCHEMBL2469601 0.71
SCHEMBL3922740 0.71
SCHEMBL20380559 0.69
Hydrochloric Acid SCHEMBL2994228 0.69
SCHEMBL19523083 0.65 HTR2A (0.33)
SCHEMBL9614345 0.64
SCHEMBL22673302 0.61 EPHX2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4466924-A Platinum-diamine complexes, a process for the preparation thereof, a process for the preparation of a medicine using such a platinum-diamine complex for the treatment of malignant tumors in mice as well as a medicine thus formed NEDERLANDSE CENTRALE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK (NL) 1984-08-21 US disclosed