⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230096 | 0.73 | TDP1 (0.53) | — | |
| SCHEMBL1666 | 0.73 | TDP1 (0.53) | — | |
| SCHEMBL11664569 | 0.73 | TDP1 (0.53) | — | |
| SCHEMBL1074337 | 0.73 | — | — | |
| SCHEMBL246946 | 0.73 | — | — | |
| SCHEMBL3838680 | 0.71 | TDP1 (0.50) | — | |
| Phosphine SCHEMBL21463026 | 0.71 | TDP1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL22230523 | 0.71 | TDP1 (0.50) | — | |
| SCHEMBL21518321 | 0.71 | TDP1 (0.50) | — | |
| SCHEMBL2153928 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440041-B1 | SYNTHESIS OF 2'-FLUORO-6'-METHYLENE-CARBOCYCLIC ADENOSINE (FMCA) AND 2'-FLUORO-6'-METHYLENE-CARBOCYCLIC GUANOSINE (FMCG) | UNIV GEORGIA (US) | 2020-11-18 | — | — | EP | claimed |
| EP-3440041-A1 | SYNTHESIS OF 2'-FLUORO-6'-METHYLENE-CARBOCYCLIC ADENOSINE (FMCA) AND 2'-FLUORO-6'-METHYLENE-CARBOCYCLIC GUANOSINE (FMCG) | University Of Georgia Research Foundation, Inc. (US) | 2019-02-13 | — | — | EP | claimed |
| WO-2017176392-A1 | SYNTHESIS OF 2'-FLUORO-6'-METHYLENE-CARBOCYCLIC ADENOSINE (FMCA) AND 2'-FLUORO-6'-METHYLENE-CARBOCYCLIC GUANOSINE (FMCG) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2017-10-12 | — | — | WO | claimed |
| CN-103073587-A | 3-sulfonic group-4-halophenyl-3'-sulfophenyl-4''-halophenylphosphine oxide and preparation method of salt thereof | UNIV TIANJIN NORMAL | 2013-05-01 | — | — | CN | disclosed |
| CN-102741237-A | Beta-dihydrofuran deriving compound, method for producing beta-dihydrofuran deriving compound or beta-tetrahydrofuran deriving compound, beta-glycoside compound, method for producing beta-glycoside compound, and method for producing 4'-ethynyl d4t and analogue comp | NISSAN CHEMICAL IND LTD | 2012-10-17 | — | — | CN | disclosed |
| CN-100434079-C | Pyrazine nucleotide/pyrazine nucleoside analogue and medical application thereof | FUJIYAMA CHEMICAL IND CO LTD (JP) | 2008-11-19 | — | — | CN | disclosed |
| CN-1551777-A | Novel virus proliferaton inhibition/virucidal method and novel pyradine nucleotide/pyradine nucleoside analogue | 富山化学工业株式会社 | 2004-12-01 | — | — | CN | disclosed |
| US-4433140-A | Tridecadeoxynucleotide, process for preparation thereof, and use thereof | DR. KARL THOMAE GMBH (DE) | 1984-02-21 | — | — | US | disclosed |