Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 4/20 | 0.41 |
| ▸ | PYGM | P11217 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126596 | 0.85 | POLB (0.55) | TYMSPOLBHPSEALDH1A1PYGL | |
| SCHEMBL17961006 | 0.84 | POLB (0.57) | TYMSPOLBHPSEALDH1A1PYGL | |
| SCHEMBL234674 | 0.82 | TYMS (0.65) | TYMSPOLBALDH1A1CA2TDP1 | |
| SCHEMBL29448334 | 0.82 | TYMS (0.65) | TYMSPOLBALDH1A1CA2TDP1 | |
| SCHEMBL29448335 | 0.82 | TYMS (0.65) | TYMSPOLBALDH1A1CA2TDP1 | |
| SCHEMBL10514322 | 0.82 | POLB (0.51) | TYMSPOLBHPSEALDH1A1PYGL | |
| Potassium SCHEMBL7487575 | 0.81 | TYMS (0.63) | TYMSPOLBALDH1A1CA2TDP1 | |
| SCHEMBL475960 | 0.78 | TYMS (0.79) | TYMSPOLBALDH1A1TDP1LMNA | |
| SCHEMBL24790646 | 0.78 | POLB (0.47) | TYMSPOLBHPSEALDH1A1PYGL | |
| SCHEMBL49365 | 0.76 | POLB (0.70) | POLBHPSEALDH1A1PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490545-A | POLYIMIDES; FILMS; COATINGS; FIBERS; MOLDING MATERIALS | STANDARD OIL COMPANY (INDIANA) (US) | 1984-12-25 | — | — | US | disclosed |
| US-4153590-A | AMPHOTERIC SURFACTANTS FOR POLYCONDENSATE RESIN SYSTEMS | CIBA-GEIGY CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |