SCHEMBL11051116

SCHEMBL11051116

CCCC(C)c1ccc2ccccc2c1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.55
CYP1A2 P05177 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP2D6 P10635 1/20 0.47
TSHR P16473 1/20 0.47
HIF1A Q16665 1/20 0.47
PPARG P37231 2/20 0.45
PPARA Q07869 2/20 0.45
CYP2A6 P11509 1/20 0.44
AOC3 Q16853 1/20 0.44
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30421518 0.94 UGT2B7 (0.48) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL2488020 0.94 UGT2B7 (0.48) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL10581782 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL10580009 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL10580172 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL10583499 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL8979859 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL10583580 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL10583623 0.86 UGT2B7 (0.49) UGT2B7CYP1A2MEN1KMT2ACYP2D6
SCHEMBL14612063 0.85 UGT2B7 (0.41) UGT2B7CYP1A2MEN1KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1147248-A N- (3-pyrrolidinyl) benzamide derivatives YAMANOUCHI PHARMA CO LTD (JP) 1997-04-09 CN disclosed
CN-1143364-A 5-HT3 receptor agonist, novel thiazole derivative, and intermediate thereof YAMANOUCHI PHARMA CO LTD (JP) 1997-02-19 CN disclosed
CN-1105354-A Novel alkamine derivative and slat of same YAMANOUCHI PHARMA CO LTD (JP) 1995-07-19 CN disclosed
CN-1051178-A New heterogeneous ring compound and preparation method thereof YAMANOUCHI PHARMA CO LTD (JP) 1991-05-08 CN disclosed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 CN disclosed
US-4459186-A Electrochemical oxidation of alkyl aromatic compounds UOP INC. (US) 1984-07-10 US disclosed