Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029089 | 0.78 | TP53 (0.50) | TP53TDP1TSHRCYP2C9CYP2C19 | |
| SCHEMBL10699373 | 0.77 | — | — | |
| SCHEMBL10901215 | 0.77 | TP53 (0.42) | TP53TDP1L3MBTL1 | |
| SCHEMBL3289373 | 0.74 | TSHR (0.48) | TP53TDP1TSHRCYP2C9CYP2C19 | |
| SCHEMBL8846669 | 0.72 | TSHR (0.46) | TP53TDP1TSHRCYP2C9CYP2C19 | |
| SCHEMBL3141511 | 0.70 | TSHR (0.43) | TP53TDP1TSHRCYP2C9CYP2C19 | |
| SCHEMBL10903123 | 0.70 | TDP1 (0.40) | TP53TDP1TSHRMEN1KMT2A | |
| SCHEMBL50875 | 0.69 | — | — | |
| SCHEMBL379577 | 0.69 | — | — | |
| SCHEMBL7533174 | 0.69 | TP53 (0.36) | TP53TDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478832-A | Pesticidal O-(N-alkoxy-substituted-benzimidoyl)-phosphorus esters and thioesters | CHEVRON RESEARCH COMPANY (US) | 1984-10-23 | — | — | US | disclosed |
| US-4473562-A | INSECTICIDE | CHEVRON RESEARCH COMPANY (US) | 1984-09-25 | — | — | US | disclosed |