Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26793524 | 0.80 | CYP19A1 (0.41) | CYP19A1CYP17A1CYP26A1KMT2A | |
| SCHEMBL425206 | 0.78 | — | — | |
| SCHEMBL9133758 | 0.78 | CYP19A1 (0.50) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| SCHEMBL22604081 | 0.78 | CYP19A1 (0.50) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| SCHEMBL21900876 | 0.78 | CYP19A1 (0.50) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| Water SCHEMBL28029306 | 0.76 | CYP19A1 (0.48) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| SCHEMBL1406898 | 0.76 | CYP19A1 (0.47) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| Iodide SCHEMBL1744365 | 0.76 | CYP19A1 (0.48) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| Hydrochloric Acid SCHEMBL28428350 | 0.76 | CYP19A1 (0.48) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 | |
| Bromide SCHEMBL28092800 | 0.76 | CYP19A1 (0.48) | CYP19A1CYP17A1CYP26A1KMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450277-A | Preparation of 1-substituted imidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-22 | — | — | US | disclosed |
| EP-0026908-B1 | PROCESS FOR PREPARING 1-SUBSTITUTED IMIDAZOLES | BASF Aktiengesellschaft (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0026908-A1 | Process for preparing 1-substituted imidazoles | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |