Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436563 | 0.86 | ACE (0.65) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL6438290 | 0.86 | ACE (0.65) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL6436560 | 0.86 | ACE (0.65) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL6438293 | 0.86 | ACE (0.65) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL19369794 | 0.82 | ACE (0.53) | ACELMNASMN1; SMN2LTA4HREN | |
| SCHEMBL10659497 | 0.82 | ACE (0.61) | ACELMNASMN1; SMN2LTA4HACE2 | |
| SCHEMBL11102814 | 0.80 | ACE (0.51) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL3472243 | 0.77 | ACE (0.60) | ACELMNASMN1; SMN2LTA4HREN | |
| SCHEMBL13111774 | 0.75 | ACE (0.80) | ACELMNASMN1; SMN2ACE2 | |
| SCHEMBL7324491 | 0.75 | ACE (0.62) | ACELMNALTA4HRENKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59227858-A | — | — | None | — | — | JP | disclosed |
| JP-S59227858-A | PROLINE DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1984-12-21 | — | — | JP | disclosed |