Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL6874605 | 1.00 | TSHR (0.57) | TSHRTHRBSLC22A1ALDH1A1TP53 | |
| Hydrogen Sulfide SCHEMBL6872592 | 1.00 | TSHR (0.57) | TSHRTHRBSLC22A1ALDH1A1TP53 | |
| SCHEMBL30518295 | 0.96 | TSHR (0.61) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL29746630 | 0.96 | TSHR (0.61) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL4187376 | 0.96 | — | — | |
| SCHEMBL3755394 | 0.96 | TSHR (0.61) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL11243531 | 0.96 | TSHR (0.61) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL1061741 | 0.96 | TSHR (0.61) | TSHRTHRBSLC22A1ALDH1A1HSD17B10 | |
| SCHEMBL8033398 | 0.96 | — | — | |
| SCHEMBL675448 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438008-A | Lubricant, containing esterified ethylene/acrylic acid or ethylene/maleic acid copolymers as the active ingredient, for moulding chlorine-containing thermoplastics | BASF AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |