Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | EYA2 | O00167 | 1/20 | 0.78 |
| ▸ | APP | P05067 | 1/20 | 0.78 |
| ▸ | ACE | P12821 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.74 |
| ▸ | DRD1 | P21728 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.74 |
| ▸ | DRD3 | P35462 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL247531 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL30569658 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL224117 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL1363382 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL10937476 | 0.94 | TDP1 (0.78) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL668797 | 0.94 | TDP1 (0.78) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL10632169 | 0.94 | TDP1 (0.78) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL2471967 | 0.94 | TDP1 (0.78) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL6418284 | 0.94 | TDP1 (0.78) | TDP1EYA2APPACEALOX15 | |
| Edetic Acid SCHEMBL10906870 | 0.94 | TDP1 (0.78) | TDP1EYA2APPACEALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4488601-A | Control of aluminum cross-linked polyacrylamides for sweep improvement | THE STANDARD OIL COMPANY (US) | 1984-12-18 | — | — | US | disclosed |