Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77642 | 0.98 | FOLH1 (0.68) | FOLH1PTPN1ALDH1A1ALOX15TSHR | |
| SCHEMBL30365583 | 0.87 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL70392 | 0.87 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL10971042 | 0.86 | FOLH1 (0.55) | FOLH1PTPN1ALDH1A1ALOX15KDM4E | |
| SCHEMBL5806456 | 0.86 | FOLH1 (0.63) | FOLH1PTPN1ALDH1A1ALOX15TSHR | |
| SCHEMBL4907779 | 0.84 | FOLH1 (0.61) | FOLH1PTPN1ALDH1A1ALOX15TSHR | |
| SCHEMBL729909 | 0.83 | FOLH1 (0.70) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| Ethylene SCHEMBL18893737 | 0.83 | FOLH1 (0.70) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL7618622 | 0.83 | FOLH1 (0.48) | FOLH1PTPN1ALDH1A1ALOX15TSHR | |
| SCHEMBL31474045 | 0.83 | FOLH1 (0.70) | FOLH1ALDH1A1ALOX15TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434178-A | ORGANOALUMINUM CHLORIDE COMPOUNDS | HOFFMANN-LA ROCHE, INC. (US) | 1984-02-28 | — | — | US | disclosed |