Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230452 | 0.79 | FGFR1 (0.59) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL4580483 | 0.77 | FGFR1 (0.58) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL19848367 | 0.77 | FGFR1 (0.59) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL11055266 | 0.77 | FGFR1 (0.53) | FGFR1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL19911344 | 0.76 | FGFR1 (0.56) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL6758619 | 0.75 | NPC1 (0.65) | FGFR1ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL19848228 | 0.75 | FGFR1 (0.55) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL18937429 | 0.75 | FGFR1 (0.55) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL9678510 | 0.74 | FGFR1 (0.47) | FGFR1ALDH1A1HTTHPGDMAPK1 | |
| SCHEMBL19848128 | 0.73 | FGFR1 (0.54) | FGFR1ALDH1A1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440933-A | HISTAMINE H2-RECEPTOR ANTAGONISTS | BRISTOL-MYERS COMPANY (US) | 1984-04-03 | — | — | US | disclosed |