SCHEMBL11054592

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](C)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	10/20	0.50

▸	CALCR	P30988	10/20	0.50

▸	GLP1R	P43220	4/20	0.47

▸	SCTR	P47872	1/20	0.47

▸	NPY5R	Q15761	3/20	0.47

▸	NPY1R	P25929	2/20	0.47

▸	NPY4R	P50391	2/20	0.47

▸	APLNR	P35414	2/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30883242	0.89	GLP1R (0.56)	RAMP3CALCRGLP1RSCTR
SCHEMBL31307935	0.89	GLP1R (0.50)	RAMP3CALCRGLP1RSCTR
SCHEMBL29964770	0.88	GLP1R (0.50)	RAMP3CALCRGLP1RSCTRAPLNR
SCHEMBL29965306	0.88	GLP1R (0.57)	RAMP3CALCRGLP1RSCTRNPY5R
SCHEMBL29964887	0.87	NPY4R (0.57)	GLP1RSCTRNPY5RNPY1RNPY4R
SCHEMBL31467531	0.86	C5AR1 (0.44)	GLP1RSCTRNPY5RNPY1RNPY4R
SCHEMBL29962070	0.86	GLP1R (0.52)	GLP1RSCTR
SCHEMBL29659772	0.86	NPY4R (0.47)	NPY5RNPY1RNPY4RAPLNR
SCHEMBL30706289	0.86	GLP1R (0.43)	RAMP3CALCRGLP1RSCTRAPLNR
SCHEMBL31236840	0.86	RAMP3 (0.48)	RAMP3CALCRGLP1RSCTRNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4438029-A	CONTROLLING SMOOTH MUSCLE CONTRACTION, HISTAMINE RELEASE, AND VASCULAR PERMEABILITY	RESEARCH CORPORATION (US)	1984-03-20	—	—	US	disclosed