SCHEMBL11054852

SCHEMBL11054852

CC(COC(=O)Cl)OC(=O)Cl

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.35
ALDH1A1 P00352 2/20 0.32
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
CHRM1 P11229 2/20 0.31
TBXA2R P21731 1/20 0.31
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30
GALR3 O60755 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28359348 0.96 TSHR (0.33) TSHRALDH1A1
Ethylene Glycol SCHEMBL10444437 0.94 TSHR (0.32) TSHR
SCHEMBL9148276 0.92 TSHR (0.31) TSHR
SCHEMBL9152793 0.92 TSHR (0.31) TSHR
SCHEMBL1745 0.82
SCHEMBL7809363 0.82 TSHR (0.42) TSHRALDH1A1LMNACYP2C9MAPT
SCHEMBL8459527 0.81
SCHEMBL5838289 0.81
SCHEMBL11167012 0.81
Hydrochloric Acid SCHEMBL28817307 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4477603-A Stable dispersions of polymers in polyfunctional active hydrogen compounds and polyurethanes based thereon THE DOW CHEMICAL COMPANY (US) 1984-10-16 US disclosed
US-4337154-A FORMED FROM A POLYALKYLENIMINE AND A NITROGEN-HETEROCYCLIC SECONDARY AMINE COMPOUND NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1982-06-29 US disclosed
US-4293503-A Synthesis of polyol bis(allyl carbonate) utilizing reagent recovery and recycle PPG INDUSTRIES, INC. (US) 1981-10-06 US disclosed
US-4200594-A INTERMEDIATES FOR POLYURATES, POLYAMIDES, AND POLYURETHANES, FIREPROOFING CLEMENT JEAN CLAUDE (FR) 1980-04-29 US disclosed
US-4176225-A FIREPROOFING CLEMENT JEAN CLAUDE (FR) 1979-11-27 US disclosed