SCHEMBL11055846

SCHEMBL11055846

C=C(C)CC(O)(CC(=C)C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
HIF1A Q16665 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.37
KCNN4 O15554 2/20 0.36
ALDH1A1 P00352 4/20 0.36
CYP2D6 P10635 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ALOX15 P16050 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
TTR P02766 1/20 0.35
KMT2A Q03164 1/20 0.35
CHRM3 P20309 1/20 0.35
HTT P42858 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15959071 0.88 CYP2C19 (0.42) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL4160841 0.88 CYP2C19 (0.42) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL18380911 0.87 CYP2C19 (0.41) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL12525234 0.87 CYP2C19 (0.41) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL121234 0.87 CYP2C19 (0.41) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL12487912 0.87 CYP2C19 (0.41) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL11922655 0.84 CYP2C19 (0.39) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL11922654 0.84 SMN1; SMN2 (0.57) CYP2C19CYP1A2CYP2C9SMN1; SMN2ALDH1A1
SCHEMBL3217031 0.84 CYP2C19 (0.39) CYP2C19CYP1A2CYP2C9HIF1ASMN1; SMN2
SCHEMBL28864314 0.78 TAAR1 (0.50) CYP2C19CYP1A2CYP2C9HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0073301-B1 PROCESS FOR THE PREPARATION OF ALPHA, BETA AND BETA, GAMMA UNSATURATED KETONES FIRMENICH SA (CH) 1984-11-21 EP disclosed
US-4453011-A BASIFICATION OF A DIALLYL CARBINOL FIRMENICH SA (CH) 1984-06-05 US disclosed
EP-0073301-A1 Process for the preparation of alpha, beta and beta, gamma unsaturated ketones FIRMENICH SA (CH) 1983-03-09 EP disclosed