Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.52 |
| ▸ | ITGAL | P20701 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30875154 | 0.88 | PDE7A (0.53) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL1403756 | 0.88 | PDE7A (0.53) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL29700437 | 0.86 | PDE7A (0.55) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL11315979 | 0.80 | PDE7A (0.46) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL7187676 | 0.76 | ITGB2 (0.80) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL2936768 | 0.76 | PDE7A (0.63) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL11016102 | 0.76 | PDE7A (0.49) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL8087222 | 0.74 | PDE7A (0.61) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL11018595 | 0.73 | PDE7A (0.46) | PDE7AITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL3249437 | 0.72 | PDE7A (0.59) | PDE7AITGB2ICAM1ITGALCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| EP-0008435-B1 | SUBSTITUTED N-PHENYL-N'-BENZOYL-THIOUREAS, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1982-05-12 | — | — | EP | disclosed |
| US-4318919-A | Combating bacteria with tetrachlorophthalamic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| EP-0024016-B1 | TETRACHLOROPHTHALAMIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR BACTERICIDAL USE | BAYER AG (DE) | 1982-02-24 | — | — | EP | disclosed |
| US-4276310-A | ARTHROPODICIDES, FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-30 | — | — | US | disclosed |
| EP-0024016-A1 | Tetrachlorophthalamic acids, process for their preparation and their bactericidal use | BAYER AG (DE) | 1981-02-18 | — | — | EP | disclosed |
| EP-0000156-B1 | 2-ARYLAMINO-3,5-DINITRO-BENZOTRIFLUORIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES. | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |
| EP-0008435-A2 | Substituted N-phenyl-N'-benzoyl-thioureas, their preparation and their use as pesticides | BAYER AG (DE) | 1980-03-05 | — | — | EP | disclosed |