Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.59 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612739 | 0.90 | TDP1 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL11468458 | 0.90 | TDP1 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL11051588 | 0.88 | TDP1 (0.68) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL22014784 | 0.87 | TDP1 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| Cefuracetime SCHEMBL615048 | 0.86 | TDP1 (0.87) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| Cefuracetime SCHEMBL615047 | 0.86 | TDP1 (0.87) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| Cefuracetime SCHEMBL11611927 | 0.86 | TDP1 (0.87) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL10916200 | 0.85 | TDP1 (0.67) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL10916202 | 0.85 | TDP1 (0.67) | TDP1NR1I2HSD17B10ALDH1A1PGR | |
| SCHEMBL11615495 | 0.84 | TDP1 (0.74) | TDP1NR1I2HSD17B10ALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465831-A | ANTIBIOTICS, BACTERICIDES | ISF S.P.A. (IT) | 1984-08-14 | — | — | US | disclosed |