Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059908 | 0.78 | TYR (0.39) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL11058933 | 0.77 | TYR (0.38) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL11058920 | 0.76 | TYR (0.40) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL2400391 | 0.76 | TYR (0.44) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL5424900 | 0.74 | TYR (0.47) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1187291 | 0.74 | TYR (0.47) | TYRCYP3A4MAPTMEN1KMT2A | |
| Bromide SCHEMBL5087885 | 0.74 | TYR (0.43) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1704787 | 0.74 | TYR (0.47) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL2400771 | 0.74 | TYR (0.47) | TYRCYP3A4MAPTMEN1KMT2A | |
| SCHEMBL1705721 | 0.74 | TYR (0.47) | TYRCYP3A4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4488992-A | Monoazo dyestuffs derived from benzothiazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-18 | — | — | US | disclosed |
| EP-0013809-A1 | Monoazo dyes of the benzothiazole series, their preparation and use in dyeing or printing hydrophobic fibres | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-08-06 | — | — | EP | disclosed |