Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060490 | 0.85 | ABL1 (0.48) | ABL1MAPT | |
| SCHEMBL11057701 | 0.84 | ABL1 (0.48) | ABL1SLC6A4MAPT | |
| SCHEMBL25736283 | 0.83 | ABL1 (0.70) | ABL1SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL25736282 | 0.83 | ABL1 (0.70) | ABL1SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL25736284 | 0.83 | ABL1 (0.70) | ABL1SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL25138507 | 0.81 | ABL1 (1.00) | ABL1MAPTSMN1; SMN2 | |
| SCHEMBL25703688 | 0.81 | ABL1 (1.00) | ABL1MAPTSMN1; SMN2 | |
| SCHEMBL11058383 | 0.80 | ABL1 (0.42) | ABL1 | |
| SCHEMBL25703526 | 0.80 | ABL1 (0.80) | ABL1MAPTSMN1; SMN2 | |
| SCHEMBL25703522 | 0.78 | ABL1 (0.76) | ABL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | claimed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |