⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405262 | 0.89 | — | — | |
| SCHEMBL1109475 | 0.85 | AAK1 (0.41) | — | |
| SCHEMBL401801 | 0.85 | — | — | |
| SCHEMBL438345 | 0.84 | — | — | |
| SCHEMBL400968 | 0.84 | — | — | |
| SCHEMBL403948 | 0.84 | — | — | |
| SCHEMBL1095750 | 0.84 | — | — | |
| SCHEMBL405712 | 0.84 | — | — | |
| SCHEMBL402850 | 0.82 | — | — | |
| SCHEMBL1095096 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153843-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100324025-A1 | Antibacterial Agents | UNIVERSITY OF WASHINGTON (US) | 2010-12-23 | — | — | US | disclosed |
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |