Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.62 |
| ▸ | REN | P00797 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PEPD | P12955 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.62 |
| ▸ | DPP4 | P27487 | 3/20 | 0.57 |
| ▸ | FAP | Q12884 | 2/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164453 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL2115244 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL19824765 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL7271951 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL8316371 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL152403 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL593691 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL2115246 | 0.98 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| Hydrogen Sulfide SCHEMBL28780209 | 0.97 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| Water SCHEMBL11063395 | 0.97 | ACE (0.62) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442030-A | ARALKYLATION WITH BENZOYLACRYLIC ACID, HYDROGENATION, ESTERIFICATION | MERCK & CO., INC. (US) | 1984-04-10 | — | — | US | disclosed |