⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057484 | 1.00 | — | — | |
| SCHEMBL21779709 | 0.75 | — | — | |
| SCHEMBL23813234 | 0.73 | — | — | |
| SCHEMBL22195128 | 0.66 | — | — | |
| SCHEMBL5316577 | 0.66 | — | — | |
| SCHEMBL12941907 | 0.66 | — | — | |
| SCHEMBL28440196 | 0.64 | — | — | |
| SCHEMBL1548215 | 0.64 | — | — | |
| SCHEMBL1548217 | 0.64 | — | — | |
| SCHEMBL13005211 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474707-A | ANTIARRHYTHMIA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4297373-A | CARDIOVASCULAR DISORDERS; ANTIARRHYTHMIA AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-10-27 | — | — | US | disclosed |