Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.73 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 7/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 3/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.46 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.46 |
| ▸ | SSU72 | Q9NP77 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912818 | 0.84 | SRC (1.00) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL11166146 | 0.84 | SRC (1.00) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL20869602 | 0.84 | SRC (1.00) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL5016643 | 0.83 | SRC (0.96) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL28406293 | 0.83 | SRC (0.96) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL28403215 | 0.83 | SRC (0.96) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL8121173 | 0.81 | SRC (0.70) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL10671823 | 0.81 | SRC (0.70) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL9912817 | 0.81 | SRC (0.70) | SRCPTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL13619014 | 0.81 | SRC (0.70) | SRCPTPN1PTPN6PTPN11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463172-A | Process for producing 2-methyl cephem-2-em and 2-methylcephem-3-em derivitaves | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0006011-B1 | CEPHALOSPORINS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0033241-A2 | Pharmaceutical compositions for rectal administration | Takeda Chemical Industries, Ltd. (JP) | 1981-08-05 | — | — | EP | disclosed |
| US-4239758-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-12-16 | — | — | US | disclosed |
| US-4238608-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-12-09 | — | — | US | disclosed |
| US-4236001-A | 7β-Acyloxy-3-heterocyclicthiomethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4218564-A | 7β-Hydroxy-3-heterocyclicthio-methyl cephalosporin intermediates | SMITHKLINE CORPORATION (US) | 1980-08-19 | — | — | US | disclosed |
| US-4172891-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1979-10-30 | — | — | US | disclosed |
| US-4158733-A | 7β-Acyloxy-3-acetoxymethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1979-06-19 | — | — | US | disclosed |
| US-4131734-A | 7β-Acyloxy-3-heterocyclicthiomethyl cephalosporins | SMITHKLINE CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
| US-4020057-A | 7β-Acyloxy cephalosporins | SMITHKLINE CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |