SCHEMBL11058970

SCHEMBL11058970

Cc1c(/N=N/c2ccc(CO)cc2)c(O)n(C)c(=O)c1C#N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 13/20 0.56
MEN1 O00255 12/20 0.56
MAPT P10636 11/20 0.56
ALDH1A1 P00352 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
PKM P14618 1/20 0.52
KDM4E B2RXH2 5/20 0.46
MITF O75030 1/20 0.46
THRB P10828 1/20 0.46
USP2 O75604 1/20 0.42
RAB9A P51151 1/20 0.42
MCL1 Q07820 1/20 0.42
TDP1 Q9NUW8 2/20 0.40
GAA P10253 1/20 0.40
LMNA P02545 1/20 0.39
PABPC1 P11940 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SAE1 Q9UBE0 1/20 0.37
UBA2 Q9UBT2 1/20 0.37
PHGDH O43175 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058973 1.00 KMT2A (0.56) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL10184550 0.85 MAPT (0.65) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL10119039 0.83 KMT2A (0.53) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL18335257 0.81 MAPT (0.54) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL18335256 0.81 MAPT (0.54) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL18269328 0.81 MAPT (0.53) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL11065074 0.80 KMT2A (0.53) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL11065070 0.80 KMT2A (0.53) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL15181350 0.79 KMT2A (0.58) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL30887207 0.79 KMT2A (0.58) KMT2AMEN1MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439513-A Color photographic light-sensitive material with naphthol redox dye releaser FUJI PHOTO FILM CO., LTD. (JP) 1984-03-27 US disclosed