Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TCF4 | P15884 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058478 | 1.00 | HTT (0.55) | HTTTCF4CTNNB1HPGDCYP19A1 | |
| SCHEMBL11058483 | 1.00 | HTT (0.55) | HTTTCF4CTNNB1HPGDCYP19A1 | |
| SCHEMBL11061106 | 0.92 | HTT (0.56) | HTTTCF4CTNNB1HPGDALDH1A1 | |
| SCHEMBL11067449 | 0.87 | HTT (0.63) | HTTHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11062021 | 0.87 | HTT (0.54) | HTTHPGDALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11064168 | 0.86 | HTT (0.59) | HTTTCF4CTNNB1HPGDALDH1A1 | |
| SCHEMBL11071119 | 0.85 | HTT (0.50) | HTTTCF4CTNNB1HPGDALDH1A1 | |
| SCHEMBL11063791 | 0.85 | HTT (0.56) | HTTTCF4CTNNB1HPGDCYP19A1 | |
| SCHEMBL11071246 | 0.85 | HTT (0.58) | HTTHPGDCYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11060647 | 0.85 | HTT (0.52) | HTTHPGDL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435394-A | 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections | SHIONOGI & CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |