Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061858 | 1.00 | MAOB (0.44) | MAOBMAOAGPR84TAAR1HRH3 | |
| SCHEMBL10900387 | 1.00 | MAOB (0.44) | MAOBMAOAGPR84TAAR1HRH3 | |
| SCHEMBL10902458 | 0.98 | MAOB (0.43) | MAOBMAOAGPR84TAAR1HRH3 | |
| SCHEMBL9059518 | 0.94 | MAOB (0.47) | MAOBMAOAGPR84TAAR1HRH3 | |
| SCHEMBL10899256 | 0.94 | MAOB (0.47) | MAOBMAOAGPR84HRH3CYP2C9 | |
| SCHEMBL9059515 | 0.94 | MAOB (0.47) | MAOBMAOAGPR84TAAR1HRH3 | |
| SCHEMBL10899249 | 0.94 | MAOB (0.47) | MAOBMAOAGPR84HRH3CYP2C9 | |
| SCHEMBL10901701 | 0.91 | MAOB (0.53) | MAOBMAOAGPR84HRH3CYP2C9 | |
| SCHEMBL11060529 | 0.91 | MAOB (0.53) | MAOBMAOAGPR84HRH3CYP2C9 | |
| SCHEMBL11060533 | 0.91 | MAOB (0.53) | MAOBMAOAGPR84HRH3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439015-A | Disubstituted ethanes | HOFFMANN-LA ROCHE INC. (US) | 1984-03-27 | — | — | US | disclosed |