Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061196 | 0.97 | PDE3B (0.74) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11062206 | 0.91 | PDE3B (0.68) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11066237 | 0.91 | PDE3B (0.67) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11065602 | 0.90 | PDE3B (0.69) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11066227 | 0.90 | PDE3B (0.66) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11058697 | 0.89 | PDE3B (0.71) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11068183 | 0.88 | PDE3B (0.70) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11067563 | 0.87 | PDE3B (0.69) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11066074 | 0.87 | PDE3B (0.71) | PDE3BPDE3APDE4DPDE4APDE4B | |
| SCHEMBL11064367 | 0.86 | PDE3B (0.70) | PDE3BPDE3APDE4DPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | claimed |
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |