Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 12/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 12/20 | 0.64 |
| ▸ | MAOA | P21397 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064663 | 0.95 | PDE3B (0.62) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL11067894 | 0.93 | PDE3B (0.75) | PDE3BPDE3A | |
| SCHEMBL11062188 | 0.93 | PDE3B (0.75) | PDE3BPDE3A | |
| SCHEMBL11061168 | 0.93 | PDE3B (0.75) | PDE3BPDE3A | |
| SCHEMBL11064367 | 0.90 | PDE3B (0.70) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL11061301 | 0.89 | PDE3B (0.69) | PDE3BPDE3A | |
| SCHEMBL11065414 | 0.87 | PDE3B (0.60) | PDE3BPDE3AMAOAMAOB | |
| SCHEMBL11064774 | 0.87 | PDE3B (0.72) | PDE3BPDE3A | |
| SCHEMBL11065042 | 0.87 | PDE3B (0.72) | PDE3BPDE3A | |
| SCHEMBL11067573 | 0.86 | PDE3B (0.71) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |