Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 11/20 | 0.62 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 6/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSH | P09668 | 1/20 | 0.58 |
| ▸ | CTSC | P53634 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11191343 | 0.99 | CAPN1 (0.61) | CAPN1CTSBCAPN9MAPK1CAPN2 | |
| SCHEMBL11065437 | 0.93 | CAPN1 (0.68) | CAPN1CTSBCAPN2CTSKCTSS | |
| SCHEMBL11063698 | 0.93 | CAPN1 (0.67) | CAPN1CTSBCAPN2CTSKCTSS | |
| SCHEMBL11069035 | 0.93 | CAPN1 (0.67) | CAPN1CTSBCAPN2CTSKCTSS | |
| Potassium Ion SCHEMBL11071633 | 0.92 | CAPN1 (0.59) | CAPN1CTSBCAPN2CTSKCTSS | |
| SCHEMBL11189319 | 0.91 | CAPN1 (0.67) | CAPN1CTSBCAPN2CTSKCTSS | |
| Potassium Ion SCHEMBL11197469 | 0.91 | CAPN1 (0.58) | CAPN1CTSBCAPN2CTSKCTSS | |
| SCHEMBL11193412 | 0.90 | CAPN1 (0.66) | CAPN1CTSBCAPN2CTSKCTSS | |
| SCHEMBL11063602 | 0.89 | CAPN1 (0.67) | CAPN1CTSBCAPN2CTSKCTSS | |
| SCHEMBL11061306 | 0.87 | CAPN1 (0.59) | CAPN1CTSBCAPN2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474800-A | PROTEASE INHIBITORS, MUSCULAR DYSTROPHY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-10-02 | — | — | US | disclosed |