SCHEMBL1106683

SCHEMBL1106683

CSc1ccc(Cc2ccc(C)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
MAPT P10636 2/20 0.60
ALDH1A1 P00352 3/20 0.51
SLC6A4 P31645 11/20 0.48
SLC6A2 P23975 3/20 0.48
SLC6A3 Q01959 3/20 0.48
LMNA P02545 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
MAOA P21397 1/20 0.47
ALOX12 P18054 1/20 0.43
SRD5A2 P31213 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026656 0.90 SLC6A4 (0.56) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL76792 0.84
SCHEMBL24380499 0.83 MAPT (0.45) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL28534675 0.83 MAPT (0.45) MEN1KMT2ANPC1RAB9AMAPT
Water SCHEMBL27813433 0.82 MEN1 (0.54) MEN1KMT2ANPC1RAB9AMAPT
Hydrochloric Acid SCHEMBL7990919 0.82 MEN1 (0.54) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL11410252 0.82 IDO1 (0.58) KMT2AALDH1A1TSHRMAPK1SRD5A2
SCHEMBL1149394 0.82 IDO1 (0.58) KMT2AALDH1A1TSHRMAPK1SRD5A2
SCHEMBL27613417 0.81 SLC6A4 (0.58) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL19631323 0.80 MEN1 (0.55) MEN1KMT2ANPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000087-B2 Thermoplastic polymer mixtures, and applications thereof SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2015-04-07 US disclosed
US-20140017966-A1 POLYPHENYLENE SULFIDE COMPOSITE FIBER AND NONWOVEN FABRIC TORAY INDUSTRIES, INC. (JP) 2014-01-16 US disclosed
US-8349974-B2 Biaxially oriented polyarylene sulfide film and method for producing the same TORAY INDUSTRIES, INC. (JP) 2013-01-08 US disclosed
US-8153732-B2 Biaxially oriented polyphenylene sulfide film TORAY INDUSTRIES, INC. (JP) 2012-04-10 US disclosed
US-20110224384-A1 Biaxially oriented polyphenylene sulfide film HIGASHIOJI TAKUJI 2011-09-15 US disclosed
US-7910655-B2 Polyarylene sulfide thermoplastic resin composition Cheil Industrial Inc. (KR) 2011-03-22 US disclosed
US-20100209712-A1 BIAXIALLY ORIENTED POLYARYLENE SULFIDE FILM AND METHOD FOR PRODUCING THE SAME TORAY INDUSTRIES, INC. (JP) 2010-08-19 US disclosed
US-7736786-B2 Composition for fuel cell bipolar plate CHEIL INDUSTRIES INC. (KR) 2010-06-15 US disclosed
US-20100144955-A1 Thermoplastic polymer mixtures, and applications thereof SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-06-10 US disclosed
US-20100048777-A1 POLYPHENYLENE SULFIDE RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-02-25 US disclosed
US-7601449-B2 Sulfonated poly(phenylene sulfide) films as polyelectrolyte membranes GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2009-10-13 US disclosed
US-7601782-B2 Composition of polyarylenesulfide, bisphenol epoxy resin and oxazoline-containing amorphous polymer DAINIPPON INK & CHEMICALS, INC. (JP) 2009-10-13 US disclosed
US-20080268322-A1 Composition for Fuel Cell Bipolar Plate CHEIL INDUSTRIES INC. (KR) 2008-10-30 US disclosed
US-20070299219-A1 Biaxially Oriented Polyarylene Sulfide Film and Laminated Polyarylene Sulfide Sheets Comprising the Same TORAY INDUSTRIES, INC. (JP) 2007-12-27 US disclosed
US-7312300-B2 Inferred water analysis in polyphenylene sulfide production CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-12-25 US disclosed
US-20070123627-A1 Polyarylene sulfide thermoplastic resin composition LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2007-05-31 US disclosed
US-7208207-B2 Liner for high pressure gas container and high pressure gas container TOYODA GOSEI CO., LTD. (JP) 2007-04-24 US disclosed