Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066878 | 1.00 | USP2 (0.40) | USP2CYP3A4RECQLBLMHSD17B10 | |
| SCHEMBL11062953 | 0.88 | MEN1 (0.34) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11062957 | 0.88 | MEN1 (0.34) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11078453 | 0.81 | GMNN (0.34) | USP2CYP3A4RECQLBLMHSD17B10 | |
| SCHEMBL3348695 | 0.79 | MEN1 (0.40) | KMT2AMEN1 | |
| SCHEMBL3348688 | 0.79 | MEN1 (0.40) | KMT2AMEN1 | |
| SCHEMBL23925493 | 0.77 | KMT2A (0.52) | USP2RECQLBLMHSD17B10GMNN | |
| SCHEMBL6469034 | 0.77 | MEN1 (0.41) | KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL31615036 | 0.77 | KMT2A (0.52) | USP2RECQLBLMHSD17B10GMNN | |
| SCHEMBL3697846 | 0.77 | KMT2A (0.52) | USP2RECQLBLMHSD17B10GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434101-A | SLOW REACTING SUBSTANCE OF ANAPHYLAXIS, ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1984-02-28 | — | — | US | disclosed |