Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17743437 | 0.98 | HRH4 (0.39) | SIGMAR1HRH4HRH3LSSFAAH | |
| SCHEMBL11064526 | 0.98 | HRH4 (0.39) | SIGMAR1HRH4HRH3LSSFAAH | |
| SCHEMBL17743439 | 0.98 | HRH4 (0.39) | SIGMAR1HRH4HRH3LSSFAAH | |
| SCHEMBL16822366 | 0.96 | HRH4 (0.36) | SIGMAR1HRH4HRH3LSSFAAH | |
| SCHEMBL17743406 | 0.94 | LSS (0.34) | SIGMAR1HRH4HRH3LSSKMT2A | |
| SCHEMBL1131900 | 0.92 | HRH4 (0.40) | SIGMAR1HRH4HRH3FAAHPHGDH | |
| SCHEMBL17743426 | 0.92 | HRH4 (0.40) | SIGMAR1HRH4HRH3FAAHPHGDH | |
| SCHEMBL9949604 | 0.90 | HRH4 (0.37) | SIGMAR1HRH4HRH3LSSFAAH | |
| SCHEMBL13306231 | 0.90 | LSS (0.40) | SIGMAR1LSSADH1AADH1CKMT2A | |
| SCHEMBL13306230 | 0.87 | LSS (0.38) | LSSADH1AADH1CKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |