Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473225 | 0.96 | PRMT1 (0.55) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL10604597 | 0.96 | PRMT1 (0.55) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL14172359 | 0.91 | TSHR (0.53) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL29440276 | 0.91 | PRMT1 (0.52) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL24483715 | 0.87 | PRMT1 (0.71) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL8766995 | 0.87 | PRMT1 (0.71) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL19646468 | 0.87 | PRMT1 (0.71) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL11468363 | 0.87 | PRMT1 (0.71) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL22506195 | 0.87 | PRMT1 (0.71) | PRMT1EPHX2ADRA1ALMNATSHR | |
| SCHEMBL17767810 | 0.87 | PRMT1 (0.71) | PRMT1EPHX2ADRA1ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120557-A2 | 21-Hydroxycorticosteroid esters, and compositions containing them | THE UPJOHN COMPANY (US) | 1984-10-03 | — | — | EP | disclosed |
| US-4472392-A | Sulfonate containing ester prodrugs of corticosteroids | THE UPJOHN COMPANY (US) | 1984-09-18 | — | — | US | disclosed |