Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | DRD2 | P14416 | 12/20 | 0.46 |
| ▸ | DRD4 | P21917 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066130 | 0.93 | PDE3B (0.53) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11066201 | 0.91 | PDE3B (0.50) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11068986 | 0.89 | PDE3B (0.51) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11062181 | 0.87 | PDE3B (0.49) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11063999 | 0.86 | PDE3B (0.54) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11064293 | 0.85 | PDE3B (0.53) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11067769 | 0.85 | PDE3B (0.51) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11069084 | 0.84 | PDE3B (0.56) | MAOAMAOBDRD2DRD4DRD3 | |
| SCHEMBL11063084 | 0.83 | MAPT (0.41) | — | |
| SCHEMBL11071318 | 0.83 | MAPT (0.41) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |