SCHEMBL110682

SCHEMBL110682

C=CC(=O)OCCCCCNCC

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.66
ALDH1A1 P00352 3/20 0.66
CYP3A4 P08684 1/20 0.66
HPGD P15428 1/20 0.59
TP53 P04637 2/20 0.46
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 1/20 0.42
KDM1A O60341 1/20 0.41
HCAR2 Q8TDS4 2/20 0.41
ATM Q13315 1/20 0.40
ACHE P22303 6/20 0.40
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9546056 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL111074 0.98 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL345430 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Hydrochloric Acid SCHEMBL6053194 0.91 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid SCHEMBL29105074 0.88 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11519959 0.88 TSHR (0.68) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10950894 0.88 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
Diethylamine SCHEMBL500593 0.86 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5366005 0.86 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11590363 0.86 TSHR (0.65) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424491-A2 FILM FORMER IN HAIR DYES Henkel AG & Co. KGaA (DE) 2012-03-07 EP disclosed
WO-2010124897-A2 FILM FORMER IN HAIR DYES HENKEL AG & CO. KGAA (DE) 2010-11-04 WO disclosed