Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37506 | 0.96 | KDM4E (0.40) | KDM4ETSHRTDP1 | |
| SCHEMBL6536446 | 0.96 | KDM4E (0.40) | KDM4ETSHRTDP1 | |
| SCHEMBL956137 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| SCHEMBL3742415 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| SCHEMBL3735353 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL956721 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| Fluoride SCHEMBL11766154 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| Potassium SCHEMBL29674780 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| SCHEMBL3736916 | 0.93 | KDM4E (0.39) | KDM4ETSHRTDP1 | |
| Iodide SCHEMBL3022858 | 0.90 | KDM4E (0.37) | KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469641-A | INTERMEDIATES FOR PERFLUOROISOPROPYLKETOCARBOXYLIC ACID FLUORIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-04 | — | — | US | disclosed |