SCHEMBL11069059

SCHEMBL11069059

Cc1ccc(C(=O)Oc2cccc(C)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.63
LMNA P02545 1/20 0.62
ALOX5 P09917 1/20 0.61
KMT2A Q03164 7/20 0.59
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
GAA P10253 2/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C19 P33261 1/20 0.56
POLB P06746 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ALDH1A1 P00352 1/20 0.53
ESR1 P03372 2/20 0.52
GBA1 P04062 1/20 0.52
ESR2 Q92731 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7211406 0.96 MAPT (0.67) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL11662446 0.93 KMT2A (0.62) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL29550597 0.90 KMT2A (0.61) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL11290345 0.90 KMT2A (0.61) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL30689549 0.89 MAPT (0.63) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL5435205 0.89 MAPT (0.63) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL1644913 0.88 MAPT (0.61) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL16247996 0.87 MAPT (0.70) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL29723825 0.87 MAPT (0.66) MAPTLMNAALOX5KMT2ACYP1A2
SCHEMBL17275083 0.86 PRSS1 (0.65) MAPTKMT2ACYP1A2CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4479138-A PHENYL BENZOIC ESTER TO INCREASE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US disclosed