Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286131 | 0.73 | NPSR1 (0.42) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL15730797 | 0.69 | NPSR1 (0.61) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL15709071 | 0.69 | NPSR1 (0.61) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL15709069 | 0.69 | NPSR1 (0.61) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL554289 | 0.68 | NPSR1 (0.48) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL598483 | 0.68 | NPSR1 (0.48) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL7772643 | 0.68 | NPSR1 (0.48) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL5455571 | 0.66 | NPSR1 (0.42) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 | |
| SCHEMBL28061117 | 0.66 | HCAR2 (0.46) | NPSR1ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL28134967 | 0.66 | NPSR1 (0.50) | NPSR1ALDH1A1SMN1; SMN2CYP2D6EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |