Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057471 | 0.91 | NPC1 (0.50) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL11073912 | 0.89 | CA12 (0.48) | NPC1KDM4EALDH1A1CA1CA2 | |
| SCHEMBL11076508 | 0.86 | NPC1 (0.48) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL11051029 | 0.86 | NPC1 (0.48) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL11076663 | 0.86 | NPC1 (0.48) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL11069439 | 0.86 | NPC1 (0.46) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL11056992 | 0.86 | NPC1 (0.43) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL10510466 | 0.85 | NPC1 (0.51) | NPC1KDM4EALDH1A1GAACA1 | |
| SCHEMBL10507288 | 0.84 | NPC1 (0.48) | NPC1KDM4EALDH1A1GAACA1 | |
| Sulfometuron Methyl SCHEMBL54998 | 0.84 | GAA (0.50) | NPC1KDM4EGAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023140-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| EP-0023140-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | claimed |
| EP-0023140-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4342587-A | Herbicidal pyridinsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0023140-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |