Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396690 | 0.82 | MGAM (0.65) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL1765966 | 0.82 | MGAM (0.65) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL4947192 | 0.79 | MGAM (0.57) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL6604149 | 0.79 | MGAM (0.57) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL610575 | 0.79 | MGAM (0.61) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL530761 | 0.79 | MGAM (0.71) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL29684771 | 0.79 | MGAM (0.71) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL28879835 | 0.79 | MGAM (0.61) | MGAMCYP1A2MAP4K4CSNK1G2CLK4 | |
| SCHEMBL2573118 | 0.78 | HTT (0.56) | CYP1A2CASP3GFERSENP8SENP7 | |
| SCHEMBL2573116 | 0.78 | HTT (0.56) | CYP1A2CASP3GFERSENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450270-A | Dioximino cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| US-4402955-A | ZWITTERIONS; GRAMNEGATIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1983-09-06 | — | — | US | disclosed |
| US-4379787-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |