Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705598 | 0.82 | HDAC3 (0.42) | MAOAMAOBCA1CA2ALDH1A1 | |
| SCHEMBL3234313 | 0.77 | ESR1 (0.56) | MAOAMAOBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10637449 | 0.77 | ESR1 (0.56) | MAOAMAOBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1391150 | 0.74 | SLC6A4 (0.53) | MAOAMAOBCA1CA2ALDH1A1 | |
| SCHEMBL13658160 | 0.74 | GFER (0.47) | MAOAMAOBCA1CA2LTA4H | |
| SCHEMBL711778 | 0.74 | MAOB (0.56) | MAOAMAOBALDH1A1KDM4EPOLB | |
| SCHEMBL22894305 | 0.74 | MEN1 (0.49) | MAOAMAOBALDH1A1POLBMAPT | |
| SCHEMBL14492421 | 0.74 | MEN1 (0.49) | MAOAMAOBALDH1A1POLBMAPT | |
| SCHEMBL5215733 | 0.74 | IDO1 (0.47) | MAOAMAOBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28642267 | 0.74 | IDO1 (0.47) | MAOAMAOBCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448935-A | CHLORO, BROMO OR HYDROXY AROMATIC CROSSLINKING AGENTS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1984-05-15 | — | — | US | claimed |