Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667884 | 1.00 | MAPT (0.43) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9667887 | 1.00 | MAPT (0.43) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9665791 | 0.95 | MAPT (0.43) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9665795 | 0.95 | MAPT (0.43) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL11075809 | 0.95 | MAPT (0.43) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9666284 | 0.92 | TDP1 (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9666277 | 0.92 | TDP1 (0.47) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10848033 | 0.92 | MAPT (0.42) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL10848031 | 0.92 | MAPT (0.42) | MAPTALDH1A1USP2CYP3A4HPGD | |
| SCHEMBL9667991 | 0.92 | TDP1 (0.42) | MAPTALDH1A1USP2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486586-A | BACTERICIDAL ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1984-12-04 | — | — | US | disclosed |