Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.59 |
| ▸ | RARA | P10276 | 2/20 | 0.59 |
| ▸ | RARG | P13631 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977419 | 1.00 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL10982640 | 1.00 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL10978571 | 1.00 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL10983282 | 1.00 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL10974844 | 1.00 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL10982386 | 1.00 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL9512344 | 0.99 | RARB (0.57) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL9512933 | 0.99 | RARB (0.57) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL11067272 | 0.94 | RARB (0.51) | RARBRARARARGS1PR1HSD17B10 | |
| SCHEMBL9399694 | 0.91 | RARB (0.59) | RARBRARARARGS1PR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490305-A | Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-12-25 | — | — | US | disclosed |
| EP-0074608-A2 | Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them | MERCK PATENT GmbH (DE) | 1983-03-23 | — | — | EP | disclosed |