Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411479 | 0.83 | ALPI (0.49) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL10411481 | 0.83 | ALPI (0.49) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL27491558 | 0.76 | ALPI (0.46) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL17844273 | 0.75 | ALPI (0.68) | CTSCALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL204285 | 0.73 | NPC1 (0.46) | — | |
| SCHEMBL19584943 | 0.72 | ALPI (0.63) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL8413750 | 0.71 | ALPI (0.50) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL8416117 | 0.71 | ALPI (0.50) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL9285110 | 0.71 | ALPI (0.61) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL9285116 | 0.71 | ALPI (0.61) | CTSCALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024664-B1 | PEPTIDE AMIDES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | claimed |
| US-4459225-A | ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| US-4459225-A | ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |