Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725165 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL6033544 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL97108 | 0.81 | HSD17B10 (0.48) | SMN1; SMN2TSHRNAPRTHSD17B10ALDH1A1 | |
| SCHEMBL55828 | 0.81 | GAA (0.42) | SMN1; SMN2TP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL11465101 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL3760045 | 0.79 | PTPN1 (0.46) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL1415961 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3996276 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11705096 | 0.78 | SCN1A (0.33) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL429187 | 0.78 | PTPN1 (0.48) | SMN1; SMN2TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426515-A | Process for the manufacture of polyurethanes by carbonylation of nitrated hydroxy-aromatic compounds | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1984-01-17 | — | — | US | disclosed |